Updated Stability for Reconstituted and Diluted Solutions of KEYTRUDA® (pembrolizumab)

Please note that the storage conditions for reconstituted and diluted solutions of KEYTRUDA® have been updated:

“The product does not contain preservative. The reconstituted and/or diluted product should be used immediately. If not used immediately, reconstituted and diluted solutions of KEYTRUDA® may be stored at room temperature for a cumulative time of up to 6 hours. Reconstituted and diluted solutions of KEYTRUDA® may also be stored under refrigeration at 2°C to 8°C; however, the total time from reconstitution or dilution of KEYTRUDA® to completion of infusion should not exceed 96 hours. If refrigerated, allow the vials and/or IV bags to come to room temperature prior to use.”

Should you have any medical questions, please call Merck Canada’s Medical Information Centre at

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