OFD 2025: Interpreting Oncology Clinical Trials 101

This session will provide a basic overview of how to evaluate and interpret the results of an oncology trial. Participants will gain an appreciation for chosen efficacy endpoints in oncology research with a focus on the interpretation of survival analyses to assess trial outcomes. The session will review key elements of critical appraisal to prepare participants to evaluate the validity, reliability, and quality of an oncology trial in their own evidence-based practice.

Learning Objectives
By the end of the session participants will be able to:

1. Appreciate the rationale for chosen efficacy endpoints in oncology trials such as progression-free survival and overall survival
2. Identify when it is most appropriate to perform a survival analysis to assess a trial outcome
3. Interpret Kaplan-Meier curves and measures of effect such as hazard ratios from oncology trials
4. Interpret the results of and critically appraise a clinical trial