ISOPP CAPhO 2025 Symposium: Aggregation of Monoclonal Antibodies in Clinical Practice: In-hospital Handling and Transport by Pneumatic Tubes

This presentation explores the risks linked to the use of commercial monoclonal antibodies in hospitals, with a focus on the impact of in-hospital handling and pneumatic tube transport. It details the methodology used to assess the effects of transport on five commonly used drugs and presents key findings. Attendees will gain insights into how transport and handling conditions can affect drug integrity and will learn approaches to assess these risks, ensuring the safety and efficacy of monoclonal antibody treatments in hospital settings.

Learning Objectives

• Identify the key risks associated with the transport and handling of monoclonal antibodies within hospital settings.
• Assess the comprehensiveness of research methodologies used to evaluate the impact of pneumatic tube transport on monoclonal antibodies.
• Describe the stability outcomes of five commonly used monoclonal antibodies after pneumatic tube transport.

Critically evaluate and propose improvements to handling and transport protocols for monoclonal antibodies in their own hospitals.